Novel Approach to Mind Wandering in Major Depressive Disorder and Bipolar Disorder Patients: Does the Direction of Thoughts Matter?

Document Type : Original Article

Authors

1 Department of Psychology, Allameh Tabatabae’i University, Tehran, Iran

2 Department of Psychology, University of Tehran, Tehran, Iran

3 Mind, Brain Imaging and Neuroethics, Institute of Mental Health Research, The Royal Mental Health Centre, University of Ottawa, Ottawa, Canada

Abstract

Abstract

Introduction: This study investigated the features of mind wandering in patients with major depressive disorder and bipolar disorder in comparison with the healthy control group.
Method: The number and duration of internally- and externally-oriented thoughts during MW in 90 healthy control, major depressive disorder, and depressed bipolar disorder subjects were measured by a novel method of experience sampling experiment in the laboratory at the Royal Mental Health Centre of the University of Ottawa, Canada using the MATLAB software. Subjects also filled out BDI-II to evaluate current depressive symptoms. The methods used to analyze data included Chi-square, ANOVA, LSD Post Hoc Test, Pearson and Spearman correlation.
Results: 1) an increased number of internally-oriented thought contents in MDD and BD; 2) the duration of time MDD and BD groups engage with the internal thoughts is almost twice the time the HC spend on it; 3) the relationship between the direction of thoughts during MW and depressive symptoms.
Conclusion: Our results show depressed patients with MDD and BD spend a longer time on internal thoughts during MW which is related to the severity of their depressive symptoms, which carries clinical implications for both diagnosis and therapy.
 

Keywords


  1. James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet. 2018;392(10159):1789-858.
  2. Kessler RC. The costs of depression. Psychiatric Clinics. 2012;35(1):1-14.
  3. Blanco C, Compton WM, Saha TD, Goldstein BI, Ruan WJ, Huang B, et al. Epidemiology of DSM-5 bipolar I disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions–III. Journal of psychiatric research. 2017;84:310-7.
  4. Steinert C, Hofmann M, Kruse J, Leichsenring F. Relapse rates after psychotherapy for depression–stable long-term effects? A meta-analysis. Journal of Affective Disorders. 2014;168:107-18.
  5. Vázquez GH, Holtzman JN, Lolich M, Ketter TA, Baldessarini RJ. Recurrence rates in bipolar disorder: systematic comparison of long-term prospective, naturalistic studies versus randomized controlled trials. European Neuropsychopharmacology. 2015;25(10):1501-12.
  6. Lorimer B, Delgadillo J, Kellett S, Lawrence J. Dynamic prediction and identification of cases at risk of relapse following completion of low-intensity cognitive behavioural therapy. Psychotherapy Research. 2020:1-14.
  7. Cuijpers P. Psychotherapies for adult depression: recent developments. Current opinion in psychiatry. 2015;28(1):24-9.
  8. Lemmens L, Van Bronswijk SC, Peeters F, Arntz A, Hollon SD, Huibers M. Long-term outcomes of acute treatment with cognitive therapy v. interpersonal psychotherapy for adult depression: follow-up of a randomized controlled trial. Psychol Med. 2019;49(3):465-73.
  9. Swartz HA, Swanson J. Psychotherapy for Bipolar Disorder in Adults: A Review of the Evidence. Focus (Am Psychiatr Publ). 2014;12(3):251-66.
  10. Association AP. Diagnostic and statistical manual of mental disorders (DSM-5®): American Psychiatric Pub; 2013.
  11. Killingsworth MA, Gilbert DT. A wandering mind is an unhappy mind. Science. 2010;330(6006):932-.
  12. McVay JC, Kane MJ, Kwapil TR. Tracking the train of thought from the laboratory into everyday life: An experience-sampling study of mind wandering across controlled and ecological contexts. Psychonomic bulletin & review. 2009;16(5):857-63.
  13. Smallwood J, Schooler JW. The restless mind. Psychological bulletin. 2006;132(6):946.
  14. Vannucci M, Chiorri C, Nocentini A, Menesini E. Distinguishing spontaneous from deliberate mind wandering in adolescents: The role of attentional control and depressive symptoms. British Journal of Developmental Psychology. 2020.
  15. Hoffmann F, Banzhaf C, Kanske P, Bermpohl F, Singer T. Where the depressed mind wanders: Self-generated thought patterns as assessed through experience sampling as a state marker of depression. Journal of affective disorders. 2016;198:127-34.
  16. Ottaviani C, Shahabi L, Tarvainen M, Cook I, Abrams M, Shapiro D. Cognitive, behavioral, and autonomic correlates of mind wandering and perseverative cognition in major depression. Frontiers in neuroscience. 2015;8:433.
  17. Seli P, Beaty RE, Marty-Dugas J, Smilek D. Depression, anxiety, and stress and the distinction between intentional and unintentional mind wandering. Psychology of Consciousness: Theory, Research, and Practice. 2019;6(2):163.
  18. Tran S. The Influence of Negative Mood on Mind Wandering as Observed Through Reach Tracking Techniques. 2019.
  19. Kane MJ, Brown LH, McVay JC, Silvia PJ, Myin-Germeys I, Kwapil TR. For whom the mind wanders, and when: An experience-sampling study of working memory and executive control in daily life. Psychological science. 2007;18(7):614-21.
  20. McVay JC, Kane MJ. Why does working memory capacity predict variation in reading comprehension? On the influence of mind wandering and executive attention. Journal of experimental psychology: general. 2012;141(2):302.
  21. Mrazek MD, Smallwood J, Schooler JW. Mindfulness and mind-wandering: finding convergence through opposing constructs. Emotion. 2012;12(3):442.
  22. Risko EF, Buchanan D, Medimorec S, Kingstone A. Everyday attention: Mind wandering and computer use during lectures. Computers & Education. 2013;68:275-83.
  23. Unsworth N, McMillan BD. Similarities and differences between mind-wandering and external distraction: A latent variable analysis of lapses of attention and their relation to cognitive abilities. Acta psychologica. 2014;150:14-25.
  24. Mooneyham BW, Schooler JW. The costs and benefits of mind-wandering: a review. Canadian Journal of Experimental Psychology/Revue canadienne de psychologie expérimentale. 2013;67(1):11.
  25. Kanske P, Schulze L, Dziobek I, Scheibner H, Roepke S, Singer T. The wandering mind in borderline personality disorder: Instability in self-and other-related thoughts. Psychiatry research. 2016;242:302-10.
  26. Van Calster L, D'Argembeau A, Salmon E, Peters F, Majerus S. Fluctuations of attentional networks and default mode network during the resting state reflect variations in cognitive states: evidence from a novel resting-state experience sampling method. Journal of Cognitive Neuroscience. 2017;29(1):95-113.
  27. Jayasinghe S. Conceptualizing Mind Wandering Using a Systems Approach: a Preliminary Exploration. Integrative Psychological and Behavioral Science. 2020:1-10.
  28. Christoff K, Irving ZC, Fox KC, Spreng RN, Andrews-Hanna JR. Mind-wandering as spontaneous thought: a dynamic framework. Nature Reviews Neuroscience. 2016;17(11):718-31.
  29. Christoff K, Gordon AM, Smallwood J, Smith R, Schooler JW. Experience sampling during fMRI reveals default network and executive system contributions to mind wandering. Proceedings of the National Academy of Sciences. 2009;106(21):8719-24.
  30. Gorgolewski KJ, Lurie D, Urchs S, Kipping JA, Craddock RC, Milham MP, et al. A correspondence between individual differences in the brain's intrinsic functional architecture and the content and form of self-generated thoughts. PloS one. 2014;9(5):e97176.
  31. Smallwood J, Schooler JW. The science of mind wandering: empirically navigating the stream of consciousness. Annual review of psychology. 2015;66:487-518.
  32. Northoff G, Magioncalda P, Martino M, Lee H-C, Tseng Y-C, Lane T. Too fast or too slow? Time and neuronal variability in bipolar disorder—A combined theoretical and empirical investigation. Schizophrenia bulletin. 2018;44(1):54-64.
  33. Vanhaudenhuyse A, Demertzi A, Schabus M, Noirhomme Q, Bredart S, Boly M, et al. Two distinct neuronal networks mediate the awareness of environment and of self. Journal of cognitive neuroscience. 2011;23(3):570-8.
  34. Dixon ML, Fox KC, Christoff K. A framework for understanding the relationship between externally and internally directed cognition. Neuropsychologia. 2014;62:321-30.
  35. Hoffmann F, Viding E, Puetz VB, Gerin MI, Sethi A, Rankin G, et al. Evidence for Depressogenic Spontaneous Thoughts and Altered Resting-State Connectivity in Adolescents With a Maltreatment History. Journal of the American Academy of Child and Adolescent Psychiatry. 2018;57(9):687-95.
  36. Marchetti I, Everaert J, Dainer-Best J, Loeys T, Beevers CG, Koster EH. Specificity and overlap of attention and memory biases in depression. Journal of affective disorders. 2018;225:404-12.
  37. First MB WJ, Karg RS, Spitzer RL. Structured Clinical Interview for DSM-5—Research Version (SCID-5 for DSM-5, Research Version; SCID-5-RV). 2015.
  38. Demertzi A, Vanhaudenhuyse A, Noirhomme Q, Faymonville M-E, Laureys S. Hypnosis modulates behavioural measures and subjective ratings about external and internal awareness. Journal of Physiology-Paris. 2015;109(4-6):173-9.
  39. Beck AT, Steer RA, Ball R, Ranieri WF. Comparison of Beck Depression Inventories–IA and –II in psychiatric outpatients. Journal of Personality Assessment. 1996;67(3):588-97.
  40. Osman A, Barrios FX, Gutierrez PM, Williams JE, Bailey J. Psychometric properties of the Beck Depression Inventory‐II in nonclinical adolescent samples. Journal of clinical psychology. 2008;64(1):83-102.
  41. Fuchs T. Depression, Intercorporeality, and Interaffectivity. Journal of Consciousness Studies. 2013;20(7-8):7-8.
  42. Northoff G. How do resting state changes in depression translate into psychopathological symptoms? From 'Spatiotemporal correspondence' to 'Spatiotemporal Psychopathology'. Current opinion in psychiatry. 2015;29:18-24.
  43. Northoff G. Is the self a higher-order or fundamental function of the brain? The “basis model of self-specificity” and its encoding by the brain’s spontaneous activity. Cognitive Neuroscience. 2016;7(1-4):203-22.
  44. Lashkary A, Karimi-Shahabi R, Hashemi T. The role of metacognitive beliefs in depression: Mediating role of rumination. International Journal of Behavioral Sciences. 2016;9(4):227-32.
  45. Yousefi z. Rumination: beginning and continuous of depression. International Journal of Behavioral Sciences. 2008;2(1):67-73.
  46. Scheibner HJ, Bogler C, Gleich T, Haynes J-D, Bermpohl F. Internal and external attention and the default mode network. Neuroimage. 2017;148:381-9.