Baqiyatallah University of Medical Sciences International Journal of Behavioral Sciences 2322-1194 15 3 2021 11 01 Effectiveness of Acceptance and Commitment Therapy on Depression, Anxiety and Cessation in Marijuana Use Disorder: A Randomized Clinical Trial 194 200 141014 10.30491/ijbs.2021.275731.1495 EN Mohammadreza Davoudi Department of clinical psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Amir Abbas Taheri Department of Counseling, Faculty of behavioral science, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Aliakbar Foroughi Department of Clinical Psychology, Kermanshah University of Medical Sciences, Kermanshah, Iran Journal Article 2021 09 13 <strong>Introduction: </strong>This study aimed to investigate the effectiveness of Acceptance and Commitment Therapy (ACT) on Marijuana Use Disorder (MUD) comorbid anxiety and depression symptoms and cessation.<br /><strong>Method:</strong> Fifty MUD patients were selected. The patients were randomly divided into interventional and control groups. The experimental group was treated with 12 weekly sessions of the ACT, and the control group received psycho education with the same duration. The tools used in this study included the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and the marijuana abstinence urine kit. Data were analyzed with SPSS (V.26).<br /><strong>Results:</strong> Abstinence rates in the ACT group compared to the control at the post-test (65% vs. 25%), and at the follow-up period (55% vs.15%) showed higher effectiveness for ACT (P<0.05). Also, among those who had lapsed, participations in the ACT group had fewer days than the control group about marijuana consuming (p <0.05). In the post-test and follow-up, anxiety and depression scores and abstinence rates in the ACT were respectively lower and higher compared to the control group (P < 0.05).<br /><strong>Conclusion: </strong>ACT can lead to lower consuming rates and a higher cessation rate in the MUD. It can also improve psychiatric symptoms in these patients. https://www.behavsci.ir/article_141014_4f6cc6332a20b9038b969dc02d481543.pdf